ECRG4 acts as a tumor suppressor gene frequently hypermethylated in human breast cancer
نویسندگان
چکیده
منابع مشابه
Down-Regulation of ECRG4, a Candidate Tumor Suppressor Gene, in Human Breast Cancer
INTRODUCTION ECRG4/C2ORF40 is a potential tumor suppressor gene (TSG) recently identified in esophageal carcinoma. Its expression, gene copy number and prognostic value have never been explored in breast cancer. METHODS Using DNA microarray and array-based comparative genomic hybridization (aCGH), we examined ECRG4 mRNA expression and copy number alterations in 353 invasive breast cancer samp...
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ژورنال
عنوان ژورنال: Bioscience Reports
سال: 2019
ISSN: 0144-8463,1573-4935
DOI: 10.1042/bsr20190087